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Short-Term Outcomes of Very Low Birth Weight Infants Born at a Tertiary Care Hospital, Istanbul, Turkey

AUTHORS

Deniz Atalay 1 , Özgül Salihoğlu 2 , * , Emrah Can 3 , Ayşegül Beşkardeş 4 , Sami Hatipoğlu 5

AUTHORS INFORMATION

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How to Cite: Atalay D, Salihoğlu &, Can E, Beşkardeş A, Hatipoğlu S. Short-Term Outcomes of Very Low Birth Weight Infants Born at a Tertiary Care Hospital, Istanbul, Turkey, Iran J Pediatr. 2013 ; 23(2):205-211.

ARTICLE INFORMATION

Iranian Journal of Pediatrics: 23 (2); 205-211
Published Online: January 24, 2012
Article Type: Research Article
Received: December 28, 2011
Accepted: November 25, 2012

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Abstract

Objective: To evaluate mortality and short-term outcomes in very low birth weight infants admitted to the tertiary neonatal intensive care unit, Istanbul, Turkey.
Methods: Study data were recorded prospectively from January 1, 2010, to December 31, 2010. The clinical findings in neonates with birth weights <1000g were compared with infants with birth weights of between 1000g and 1499g.
Findings: In the present study, survival rates were 40% and 86.2% for infants weighing <1000g and 1000g to 1499g, respectively. There was no difference between males and females with respect to mortality (P>0.05). The mean (±standard deviation) birth weight was 985.6±150.15 g and mean gestational age was 27.5±2.04 weeks. The antenatal steroid rate was 37.2%, and the Cesarean section rate was 73%. Respiratory distress syndrome was diagnosed in 89% of the infants, with a 69% surfactant administration rate. Severe intracranial hemorrhage (IVH) (grade >II) was 14%. Grade 4 periventricular leukomalacia was 10%. Twelve (24%) infants had evidence of bronchopulmonary dysplasia (BPD). Retinopathy of prematurity (stage >II) was 4%. The correlation between ROP rate and need for ventilation therapy was present (r=0.52). Proven necrotizing enterocolitis (stage >2) was not observed. Patent ductus arteriosus (PDA) was diagnosed in 67% of the neonates. BPD, IVH, and PDA were statistically higher in neonates with a birth weight <1000g.
Conclusion: Survival rate of VLBW infants increased with increasing BW. Sex was not a risk factor for mortality. The need for ventilatory therapy may be an important risk factor for ROP in infants <1500g.

 

Keywords

Mortality Morbidity Neonate Very Low Birth Weight

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