Iranian Journal of Pediatrics

Published by: Kowsar

Eradication of Helicobacter pylori in Children by Triple Therapy Regimens of Amoxicillin, Omeprazole, and Clarithromycin or Azithromycin

Mohammad Reza Esmaeili-Dooki 1 , Hossein Shirdel 1 , * and Mahmood Hajiahmadi 1
Authors Information
1 Non-Communicable Pediatric Diseases Research Center, Amirkola Children’s Hospital, Babol University of Medical Sciences, Babol, IR Iran
Article information
  • Iranian Journal of Pediatrics: December 28, 2015, 25 (6); e2360
  • Published Online: December 23, 2015
  • Article Type: Research Article
  • Received: May 19, 2015
  • Revised: September 1, 2015
  • Accepted: September 28, 2015
  • DOI: 10.5812/ijp.2360

To Cite: Esmaeili-Dooki M R, Shirdel H, Hajiahmadi M. Eradication of Helicobacter pylori in Children by Triple Therapy Regimens of Amoxicillin, Omeprazole, and Clarithromycin or Azithromycin, Iran J Pediatr. 2015 ;25(6):e2360. doi: 10.5812/ijp.2360.

Abstract
Copyright © 2015, Growth & Development Research Center.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
Acknowledgements
References
  • 1. Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med. 2002; 347(15): 1175-86[DOI][PubMed]
  • 2. Vale FF, Vitor JM. Transmission pathway of Helicobacter pylori: does food play a role in rural and urban areas? Int J Food Microbiol. 2010; 138(1-2): 1-12[DOI][PubMed]
  • 3. Torres J, Pérez-Pérez G, Goodman KJ, Atherton JC, Gold BD, Harris PR, et al. A Comprehensive Review of the Natural History of Helicobacter pylori Infection in Children. Arch Med Res. 2000; 31(5): 431-69[DOI]
  • 4. Blanchard SS, Bauman L, Czinn SJ. Treatment of Helicobacter pylori in Pediatrics. Curr Treat Options Gastroenterol. 2004; 7(5): 407-12[PubMed]
  • 5. Jafar S, Jalil A, Soheila N, Sirous S. Prevalence of helicobacter pylori infection in children, a population-based cross-sectional study in west iran. Iran J Pediatr. 2013; 23(1): 13-8[PubMed]
  • 6. Rodrigues MN, Queiroz DM, Bezerra Filho JG, Pontes LK, Rodrigues RT, Braga LL. Prevalence of Helicobacter pylori infection in children from an urban community in north-east Brazil and risk factors for infection. Eur J Gastroenterol Hepatol. 2004; 16(2): 201-5[PubMed]
  • 7. Raymond J, Bergeret M, Kalach N. [Helicobacter pylori infection in children]. Presse Med. 2008; 37(3 Pt 2): 513-8[DOI][PubMed]
  • 8. Levine TS, Price AB. Helicobacter pylori: enough to give anyone an ulcer! Br J Clin Pract. 1993; 47(6): 328-32[PubMed]
  • 9. Malfertheiner P, Megraud F, O'Morain C, Bazzoli F, El-Omar E, Graham D, et al. Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report. Gut. 2007; 56(6): 772-81[DOI][PubMed]
  • 10. Perri F, Qasim A, Marras L, O'Morain C. Treatment of Helicobacter pylori infection. Helicobacter. 2003; 8 Suppl 1: 53-60[PubMed]
  • 11. Das JC, Paul N. Epidemiology and pathophysiology of Helicobacter pylori infection in children. Indian J Pediatr. 2007; 74(3): 287-90[DOI]
  • 12. Sun WH, Ou XL, Cao DZ, Yu Q, Yu T, Hu JM, et al. Efficacy of omeprazole and amoxicillin with either clarithromycin or metronidazole on eradication of Helicobacter pylori in Chinese peptic ulcer patients. World J Gastroenterol. 2005; 11(16): 2477-81[PubMed]
  • 13. Gisbert JP. Rescue Therapy for Helicobacter pylori Infection 2012. Gastroenterol Res Pract. 2012; 2012: 974594[DOI][PubMed]
  • 14. Megraud F, Darmaillac V, Brügmann D. Helicobacter pylori and azithromycin. Pathologie-biologie. 1995; 43(6): 555-60
  • 15. Silva FM, Eisig JN, Teixeira AC, Barbuti RC, Navarro-Rodriguez T, Mattar R. Short-term triple therapy with azithromycin for Helicobacter pylori eradication: low cost, high compliance, but low efficacy. BMC Gastroenterol. 2008; 8: 20[DOI][PubMed]
  • 16. Caselli M, Trevisani L, Tursi A, Sartori S, Ruina M, Luzzi I, et al. Short-term low-dose triple therapy with azithromycin, metronidazole and lansoprazole appears highly effective for the eradication of Helicobacter pylori. Eur J Gastroenterol Hepatol. 1997; 9(1): 45-8[PubMed]
  • 17. Di Mario F, Dal Bo N, Grassi SA, Rugge M, Cassaro M, Donisi PM, et al. Azithromycin for the cure of Helicobacter pylori infection. Am J Gastroenterol. 1996; 91(2): 264-7[PubMed]
  • 18. Bertoni G, Sassatelli R, Nigrisoli E, Tansini P, Bianchi G, Della Casa G, et al. Triple therapy with azithromycin, omeprazole, and amoxicillin is highly effective in the eradication of Helicobacter pylori: a controlled trial versus omeprazole plus amoxicillin. Am J Gastroenterol. 1996; 91(2): 258-63[PubMed]
  • 19. Dong J, Yu XF, Zou J. Azithromycin-containing versus standard triple therapy for Helicobacter pylori eradication: a meta-analysis. World J Gastroenterol. 2009; 15(48): 6102-10[PubMed]
  • 20. Najafi M, Sobhani M, Khodadad A, Farahmand F, Motamed F. Reinfection Rate after Successful Helicobacter pylori Eradication in Children. Iran J Pediatr. 2010; 20(1): 58-62[PubMed]
  • 21. Ahmad K, Fatemeh F, Mehri N, Maryam S. Probiotics for the treatment of pediatric helicobacter pylori infection: a randomized double blind clinical trial. Iran J Pediatr. 2013; 23(1): 79-84[PubMed]
  • 22. Iranikhah A, Ghadir MR, Sarkeshikian S, Saneian H, Heiari A, Mahvari M. Stool antigen tests for the detection of Helicobacter pylori in children. Iran J Pediatr. 2013; 23(2): 138-42[PubMed]
  • 23. Kazemi S, Tavakkoli H, Habizadeh MR, Emami MH. Diagnostic values of Helicobacter pylori diagnostic tests: stool antigen test, urea breath test, rapid urease test, serology and histology. J Res Med Sci. 2011; 16(9): 1097-104[PubMed]
  • 24. Vaira D, Malfertheiner P, Megraud F, Axon AT, Deltenre M, Gasbarrini G, et al. Noninvasive antigen-based assay for assessing Helicobacter pylori eradication: a European multicenter study. The European Helicobacter pylori HpSA Study Group. Am J Gastroenterol. 2000; 95(4): 925-9[DOI][PubMed]
  • 25. Sarkeshikian SS, Iranikhah A, Ghadir MR. Azithromycin based triple therapy versus standard clarithromycin based triple therapy in eradication of Helicobacter pylori infection in Iran: a randomized controlled clinical trial. Turk J Gastroenterol. 2013; 24(1): 10-4[PubMed]
  • 26. Sullivan B, Coyle W, Nemec R, Dunteman T. Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. Am J Gastroenterol. 2002; 97(10): 2536-9[DOI][PubMed]
  • 27. Bahremand S, Zamani A, Foroutan H, Tirgari F, Nooripour S, Razavi L, et al. EVALUATION OF TRIPLE AND QUADRUPLE REGIMENS IN ERADICATION OF HELICOBACTER PYLORI INFECTION IN PEDIATRIC PATIENTS IN EMAM KHOMEINI HOSPITAL IN 2002-2003: A RANDOMIZED CLINICAL TRIAL. Med J Islam Republic Iran . 2005; 19(1): 29-33
  • 28. Kato S, Takeyama J, Ebina K, Naganuma H. Omeprazole-based dual and triple regimens for Helicobacter pylori eradication in children. Pediatrics. 1997; 100(1)[PubMed]
  • 29. Mosleh MN, Gharibi M, Alikhani MY, Saidijam M, Vakhshiteh F. Antimicrobial susceptibility and analysis of macrolide resistance genes in Streptococcus pneumoniae isolated in Hamadan. Iran J Basic Med Sci. 2014; 17(8): 595-9[PubMed]
  • 30. Shahcheraghi F, Nakhost Lotfi M, Nikbin VS, Shooraj F, Azizian R, Parzadeh M, et al. The First Macrolide-Resistant Bordetella pertussis Strains Isolated From Iranian Patients. Jundishapur J Microbiol. 2014; 7(6)[DOI][PubMed]
  • 31. Mohammadi M, Doroud D, Mohajerani N, Massarrat S. Helicobacter pylori antibiotic resistance in Iran. World J Gastroenterol. 2005; 11(38): 6009-13[PubMed]
  • 32. Milani M, Ghotaslou R, Akhi MT, Nahaei MR, Hasani A, Somi MH, et al. The status of antimicrobial resistance of Helicobacter pylori in Eastern Azerbaijan, Iran: comparative study according to demographics. J Infect Chemother. 2012; 18(6): 848-52[DOI][PubMed]
  • 33. Khademi F, Poursina F, Hosseini E, Akbari M, Safaei HG. Helicobacter pylori in Iran: A systematic review on the antibiotic resistance. Iran J Basic Med Sci. 2015; 18(1): 2-7[PubMed]
  • 34. Falsafi T, Sotoudeh N, Feizabadi MM, Mahjoub F. Analysis of Genomic Diversity among Helicobacter pylori Strains Isolated from Iranian Children by Pulsed Field Gel Electrophoresis. Iran J Pediatr. 2014; 24(6): 703-9[PubMed]
  • 35. Chuah SK, Tsay FW, Hsu PI, Wu DC. A new look at anti-Helicobacter pylori therapy. World J Gastroenterol. 2011; 17(35): 3971-5[DOI][PubMed]
  • 36. Montague S, O'Morain CA. Novel therapeutic approaches to the management of Helicobacter pylori infection. Ital J Gastroenterol Hepatol. 1998; 30 Suppl 3-8[PubMed]
  • 37. Rafeey M, Ghotaslou R, Milani M, Farokhi N, Ghojazadeh M. Association between Helicobacter pylori, cagA, and vacA Status and Clinical Presentation in Iranian Children. Iran J Pediatr. 2013; 23(5): 551-6[PubMed]
  • 38. Minakari M, Davarpanah Jazi AH, Shavakhi A, Moghareabed N, Fatahi F. A randomized controlled trial: efficacy and safety of azithromycin, ofloxacin, bismuth, and omeprazole compared with amoxicillin, clarithromycin, bismuth, and omeprazole as second-line therapy in patients with Helicobacter pylori infection. Helicobacter. 2010; 15(2): 154-9[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments