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Transfusion-Associated HIV Infection in Pediatric Leukemia Patients (Two Case Reports)

AUTHORS

Shilong Yang 1 , Yongmin Tang 1 , Hua Song 1 , Mingming Zhou 2 , Xuejun Chen 2 , Botao Ning 1 , *

1 Division of Hematology-Oncology, Children's Hospital, Zhejiang University School of Medicine, China

2 Division of Clinical Laboratory, Children's Hospital, Zhejiang University School of Medicine, Zhejiang, China

How to Cite: Yang S, Tang Y, Song H, Zhou M, Chen X, et al. Transfusion-Associated HIV Infection in Pediatric Leukemia Patients (Two Case Reports), Iran J Pediatr. 2015 ; 22(3):412-416.

ARTICLE INFORMATION

Iranian Journal of Pediatrics: 22 (3); 412-416
Published Online: September 30, 2012
Article Type: Case Report
Received: December 03, 2010
Accepted: November 20, 2011

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Abstract

Background: Background: Congenital insensitivity to pain with anhidrosis (CIPA) is characterized by recurrent episodes of infections and unexplained fever, anhidrosis (inability to sweat), and absence of reaction to noxious stimuli, self-mutilating behavior, mental retardation and damages to oral structures.
Case Presentation: In this article, we have demonstrated the signs and symptoms of 4 children that refer to the pediatrics department of the Imam Khomeini hospital and assay about their complications with this disease. They mostly presented by recurrent osteomyelitis in their feet that severely controlled by antibiotic therapy and even surgery. They had no pain sensation in spite of deep sore and infection.
Conclusion: This syndrome can be diagnosed by clinical and paraclinical tests together but it would be better to confirm by genetic test. The diagnosis of this syndrome helps us to try for the better quality of life for the patients and avoid unnecessary amputations.

 

Keywords

HIV Blood Treansfusion Leukemia AIDS

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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