Iranian Journal of Pediatrics

Published by: Kowsar

Primary Antibiotic Resistance to Helicobacter pylori Strains Isolated From Children in Northern Iran: A Single Center Study

Shohreh Maleknejad 1 , * , Ali Mojtahedi 1 , Afshin Safaei-Asl 1 , Zeinab Taghavi 1 and Ehsan Kazemnejad 1
Authors Information
1 Department of Pediatrics, 17th Shahrivar Hospital, Guilan University of Medical Sciences, Rasht, IR Iran
Article information
  • Iranian Journal of Pediatrics: December 28, 2015, 25 (6); e2661
  • Published Online: December 23, 2015
  • Article Type: Research Article
  • Received: June 3, 2015
  • Revised: August 25, 2015
  • Accepted: September 5, 2015
  • DOI: 10.5812/ijp.2661

To Cite: Maleknejad S, Mojtahedi A, Safaei-Asl A, Taghavi Z, Kazemnejad E. Primary Antibiotic Resistance to Helicobacter pylori Strains Isolated From Children in Northern Iran: A Single Center Study, Iran J Pediatr. 2015 ; 25(6):e2661. doi: 10.5812/ijp.2661.

Copyright © 2015, Growth & Development Research Center.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Marcdante K, Kliegman RM, Behrman RE, Jenson HB. Nelson essentials of pediatrics. 2010;
  • 2. Sykora J, Rowland M. Helicobacter pylori in pediatrics. Helicobacter. 2011; 16 Suppl 1: 59-64[DOI][PubMed]
  • 3. Calvet X, Ramirez Lazaro MJ, Lehours P, Megraud F. Diagnosis and epidemiology of Helicobacter pylori infection. Helicobacter. 2013; 18 Suppl 1: 5-11[DOI][PubMed]
  • 4. Megraud F. H pylori antibiotic resistance: prevalence, importance, and advances in testing. Gut. 2004; 53(9): 1374-84[DOI][PubMed]
  • 5. Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group. Gut. 1997; 41(1): 8-13[DOI]
  • 6. Jason LA, Pokorny SB, Adams M, Nihls A, Kim HY, Hunt Y. Cracking Down On Youth Tobacco May Influence Drug Use. J Community Psychol. 2010; 38(1): 1-15[DOI][PubMed]
  • 7. Siavoshi F, Safari F, Doratotaj D, Khatami GR, Fallahi GH, Mirnaseri MM. Antimicrobial resistance of Helicobacter pylori isolates from Iranian adults and children. Arch Iran Med. 2006; 9(4): 308-14[PubMed]
  • 8. Eyvazi S, Hakemi-Vala M. A Review Article on Helicobacter pylori Antibiotic Resistance Profile in Iran. Int J Trop Dis Health. 2015; 10(1): 1-12[DOI]
  • 9. Khademi F, Poursina F, Hosseini E, Akbari M, Safaei HG. Helicobacter pylori in Iran: A systematic review on the antibiotic resistance. Iran J Basic Med Sci. 2015; 18(1): 2-7[PubMed]
  • 10. Kato S, Fujimura S, Udagawa H, Shimizu T, Maisawa S, Ozawa K, et al. Antibiotic resistance of Helicobacter pylori strains in Japanese children. J Clin Microbiol. 2002; 40(2): 649-53[PubMed]
  • 11. Koletzko S, Richy F, Bontems P, Crone J, Kalach N, Monteiro ML, et al. Prospective multicentre study on antibiotic resistance of Helicobacter pylori strains obtained from children living in Europe. Gut. 2006; 55(12): 1711-6[DOI][PubMed]
  • 12. Milani M, Ghotaslou R, Akhi MT, Nahaei MR, Hasani A, Somi MH, et al. The status of antimicrobial resistance of Helicobacter pylori in Eastern Azerbaijan, Iran: comparative study according to demographics. J Infect Chemother. 2012; 18(6): 848-52[DOI][PubMed]
  • 13. Rafeey M, Ghotaslou R, Nikvash S, Hafez AA. Primary resistance in Helicobacter pylori isolated in children from Iran. J Infect Chemother. 2007; 13(5): 291-5[DOI][PubMed]
  • 14. Fallahi GH, Maleknejad S. Helicobacter pylori culture and antimicrobial resistance in Iran. Indian J Pediatr. 2007; 74(2): 127-30[DOI]
  • 15. Alborzi A, Soltani J, Pourabbas B, Oboodi B, Haghighat M, Hayati M, et al. Prevalence of Helicobacter pylori infection in children (south of Iran). Diagn Microbiol Infect Dis. 2006; 54(4): 259-61[DOI][PubMed]
  • 16. Falsafi T, Mobasheri F, Nariman F, Najafi M. Susceptibilities to different antibiotics of Helicobacter pylori strains isolated from patients at the pediatric medical center of Tehran, Iran. J Clin Microbiol. 2004; 42(1): 387-9[PubMed]
  • 17. Haghi Tomatari F, Mohabbati Mobarez A, Amini M, Hosseini D, Abadi ATB. Helicobacter pylori resistance to metronidazole and clarithromycin in dyspeptic patients in Iran. Iran Red Crescent Med J. 2010; 12(4): 409
  • 18. Mohammadi M, Doroud D, Mohajerani N, Massarrat S. Helicobacter pylori antibiotic resistance in Iran. World J Gastroenterol. 2005; 11(38): 6009-13[PubMed]
  • 19. Naserpour Farivar T, Najafipour R, Johari P. Prevalence of clarithromycin-resistant Helicobacter pylori in patients with chronic tonsillitis by allele-specific Scorpion real-time polymerase chain reaction assay. Laryngoscope. 2013; 123(6): 1478-82[DOI][PubMed]
  • 20. Sherif M, Mohran Z, Fathy H, Rockabrand DM, Rozmajzl PJ, Frenck RW. Universal high-level primary metronidazole resistance in Helicobacter pylori isolated from children in Egypt. J Clin Microbiol. 2004; 42(10): 4832-4[DOI][PubMed]
  • 21. Oleastro M, Cabral J, Ramalho PM, Lemos PS, Paixao E, Benoliel J, et al. Primary antibiotic resistance of Helicobacter pylori strains isolated from Portuguese children: a prospective multicentre study over a 10 year period. J Antimicrob Chemother. 2011; 66(10): 2308-11[DOI][PubMed]
  • 22. Kalach N, Serhal L, Asmar E, Campeotto F, Bergeret M, Dehecq E, et al. Helicobacter pylori primary resistant strains over 11 years in French children. Diagn Microbiol Infect Dis. 2007; 59(2): 217-22[DOI][PubMed]
  • 23. Vecsei A, Kipet A, Innerhofer A, Graf U, Binder C, Gizci H, et al. Time trends of Helicobacter pylori resistance to antibiotics in children living in Vienna, Austria. Helicobacter. 2010; 15(3): 214-20[DOI][PubMed]
  • 24. Nguyen TV, Bengtsson C, Yin L, Nguyen GK, Hoang TT, Phung DC, et al. Eradication of Helicobacter pylori in children in Vietnam in relation to antibiotic resistance. Helicobacter. 2012; 17(4): 319-25[DOI][PubMed]
  • 25. Torres J, Camorlinga-Ponce M, Perez-Perez G, Madrazo-De la Garza A, Dehesa M, Gonzalez-Valencia G, et al. Increasing multidrug resistance in Helicobacter pylori strains isolated from children and adults in Mexico. J Clin Microbiol. 2001; 39(7): 2677-80[DOI][PubMed]
  • 26. Manfredi M, Gismondi P, Maffini V, Bizzarri B, Fornaroli F, Madia C, et al. Primary Antimicrobial Susceptibility Changes in Children with Helicobacter pylori Infection over 13 Years in Northern Italy. Gastroenterol Res Pract. 2015; 2015: 717349[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments