Iranian Journal of Pediatrics

Published by: Kowsar

Analysis of Outcome of Intraplueral Streptokinase in Pediatric Empyema Thoracis even in Advanced Stages: A Prospective Study

Kallol Bose 1 , * , Sudip Saha 2 , Dhrubojyoti Mridha 1 , Kallol Das 3 , Piyasi Mondal 3 and Ira Das 3
Authors Information
1 Assistant Professor, Pediatrics Chittaranjan Seva Sadan Hospital, Kolkata, India
2 Associate Professor, Pediatrics Chittaranjan Seva Sadan Hospital, Kolkata, India
3 RMO cum CT, Pediatrics Chittaranjan Seva Sadan Hospital, Kolkata, India
Article information
  • Iranian Journal of Pediatrics: October 28, 2015, 25 (5); e3154
  • Published Online: October 6, 2015
  • Article Type: Research Article
  • Received: June 27, 2015
  • Revised: July 13, 2015
  • Accepted: August 16, 2015
  • DOI: 10.5812/ijp.3154

To Cite: Bose K, Saha S, Mridha D, Das K, Mondal P, et al. Analysis of Outcome of Intraplueral Streptokinase in Pediatric Empyema Thoracis even in Advanced Stages: A Prospective Study, Iran J Pediatr. 2015 ;25(5):e3154. doi: 10.5812/ijp.3154.

Abstract
Copyright © 2015, Growth & Development Research Center.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
References
  • 1. Strachan R, Jaffe A, Australian Research Network in E. Assessment of the burden of paediatric empyema in Australia. J Paediatr Child Health. 2009; 45(7-8): 431-6[PubMed]
  • 2. Jaffe A, Balfour-Lynn IM. Management of empyema in children. Pediatr Pulmonol. 2005; 40(2): 148-56[DOI][PubMed]
  • 3. Bekri H, Cohen R, Varon E, Madhi F, Gire R, Guillot F, et al. [Streptococcus pneumoniae serotypes involved in children with pleural empyemas in France]. Arch Pediatr. 2007; 14(3): 239-43[DOI][PubMed]
  • 4. Byington CL, Spencer LY, Johnson TA, Pavia AT, Allen D, Mason EO, et al. An epidemiological investigation of a sustained high rate of pediatric parapneumonic empyema: risk factors and microbiological associations. Clin Infect Dis. 2002; 34(4): 434-40[DOI][PubMed]
  • 5. Byington CL, Korgenski K, Daly J, Ampofo K, Pavia A, Mason EO. Impact of the pneumococcal conjugate vaccine on pneumococcal parapneumonic empyema. Pediatr Infect Dis J. 2006; 25(3): 250-4[DOI][PubMed]
  • 6. Calbo E, Garau J. Invasive pneumococcal disease in children: changing serotypes and clinical expression of disease. Clin Infect Dis. 2005; 41(12): 1821-2[DOI][PubMed]
  • 7. Calbo E, Diaz A, Canadell E, Fabrega J, Uriz S, Xercavins M, et al. Invasive pneumococcal disease among children in a health district of Barcelona: early impact of pneumococcal conjugate vaccine. Clin Microbiol Infect. 2006; 12(9): 867-72[DOI][PubMed]
  • 8. Fletcher M, Leeming J, Cartwright K, Finn A, South West of England Invasive Community Acquired Infection Study G. Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2006; 25(6): 559-60[DOI][PubMed]
  • 9. Gupta R, Crowley S. Increasing paediatric empyema admissions. Thorax. 2006; 61(2): 179-80[DOI][PubMed]
  • 10. Obando I, Arroyo LA, Sanchez-Tatay D, Moreno D, Hausdorff WP, Brueggemann AB. Molecular typing of pneumococci causing parapneumonic empyema in Spanish children using multilocus sequence typing directly on pleural fluid samples. Pediatr Infect Dis J. 2006; 25(10): 962-3[DOI][PubMed]
  • 11. Obando I, Arroyo LA, Sanchez-Tatay D, Tarrago D, Moreno D, Hausdorff WP, et al. Molecular epidemiology of paediatric invasive pneumococcal disease in southern Spain after the introduction of heptavalent pneumococcal conjugate vaccine. Clin Microbiol Infect. 2007; 13(3): 347-8[DOI][PubMed]
  • 12. Roxburgh CS, Youngson GG, Townend JA, Turner SW. Trends in pneumonia and empyema in Scottish children in the past 25 years. Arch Dis Child. 2008; 93(4): 316-8[DOI][PubMed]
  • 13. Singleton RJ, Hennessy TW, Bulkow LR, Hammitt LL, Zulz T, Hurlburt DA, et al. Invasive pneumococcal disease caused by nonvaccine serotypes among alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage. JAMA. 2007; 297(16): 1784-92[DOI][PubMed]
  • 14. Spencer DA, Iqbal SM, Hasan A, Hamilton L. Empyema thoracis is still increasing in UK children. BMJ. 2006; 332(7553): 1333[DOI][PubMed]
  • 15. Eastham KM, Freeman R, Kearns AM, Eltringham G, Clark J, Leeming J, et al. Clinical features, aetiology and outcome of empyema in children in the north east of England. Thorax. 2004; 59(6): 522-5[PubMed]
  • 16. Playfor SD, Smyth AR, Stewart RJ. Increase in incidence of childhood empyema. Thorax. 1997; 52(10): 932[PubMed]
  • 17. Glenna B, Lossef SV. Nelson Textbook of Pediatrics. 2011; : 1507
  • 18. Atikun Limsukon. . Parapneumonic Pleural Effusions and Empyema Thoracis Treatment & Management.
  • 19. Menon P, Kanojia RP, Rao KL. Empyema thoracis: Surgical management in children. J Indian Assoc Pediatr Surg. 2009; 14(3): 85-93[DOI][PubMed]
  • 20. Ulku R, Onat S, Kilic N. Intrapleural fibrinolytic treatment of multiloculated pediatric empyemas. Minerva Pediatr. 2004; 56(4): 419-23[PubMed]
  • 21. Doski JJ, Lou D, Hicks BA, Megison SM, Sanchez P, Contidor M, et al. Management of parapneumonic collections in infants and children. J Pediatr Surg. 2000; 35(2): 265-8[PubMed]
  • 22. Sonnappa S, Cohen G, Owens CM, van Doorn C, Cairns J, Stanojevic S, et al. Comparison of urokinase and video-assisted thoracoscopic surgery for treatment of childhood empyema. Am J Respir Crit Care Med. 2006; 174(2): 221-7[DOI][PubMed]
  • 23. Thomson AH, Hull J, Kumar MR, Wallis C, Balfour Lynn IM. Randomised trial of intrapleural urokinase in the treatment of childhood empyema. Thorax. 2002; 57(4): 343-7[PubMed]
  • 24. Khan N, Mian I, Javed A, Wazir S, Yousaf M. Efficacy, safety and tolerability of streptokinase in multiloculated empyema. J Ayub Med Coll Abbottabad. 2003; 15(4): 20-2[PubMed]
  • 25. Nie W, Liu Y, Ye J, Shi L, Shao F, Ying K, et al. Efficacy of intrapleural instillation of fibrinolytics for treating pleural empyema and parapneumonic effusion: a meta-analysis of randomized control trials. Clin Respir J. 2014; 8(3): 281-91[DOI][PubMed]
  • 26. Ekingen G, Guvenc BH, Sozubir S, Tuzlaci A, Senel U. Fibrinolytic treatment of complicated pediatric thoracic empyemas with intrapleural streptokinase. Eur J Cardiothorac Surg. 2004; 26(3): 503-7[DOI][PubMed]
  • 27. Chai FY, Kuan YC. Massive hemothorax following administration of intrapleural streptokinase. Ann Thorac Med. 2011; 6(3): 149-51[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments