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Reversible Cataract as the Presenting Sign of Diabetes Mellitus: Report of Two Cases and Literature Review

AUTHORS

Xiu Min Wang 1 , Yan Yan Jin 1 , Ke Huang 1 , Chao Chun Zou 1 , Li Liang 1 , *

1 Department of Endocrinology, Children’s Hospital of Zhejiang University School of Medicine, China

How to Cite: Min Wang X, Yan Jin Y, Huang K, Chun Zou C, Liang L. Reversible Cataract as the Presenting Sign of Diabetes Mellitus: Report of Two Cases and Literature Review, Iran J Pediatr. 2016 ; 22(1):125-128.

ARTICLE INFORMATION

Iranian Journal of Pediatrics: 22 (1); 125-128
Published Online: March 31, 2012
Article Type: Case Report
Received: February 02, 2010
Accepted: May 27, 2011

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Abstract

Background: Type 1 diabetes mellitus (T1DM) is the most common form of diabetes in young children. Serious optic complications, e.g. diabetic retinopathy and diabetic cataract involvement, are not usually detected in T1DM patients at the onset of the disease.
Case Presentation: Two girls aged 11 years and 9 years were hospitalized in our unit in 2008 and 2009. They presented cataracts 1 and 6 months before the diagnosis of T1DM, respectively. After blood glucose level was controlled by insulin therapy, the cataract was resolved, totally in one and partly in the other girl. Meanwhile, visual acuity of both cases recovered, closely associated with fluctuation of plasma glucose level. In this study, we describe the symptoms, probable mechanism and treatment of diabetic cataract.
Conclusion: Early antihyperglycemic therapy and maintenance of stable blood glucose level may reverse acute diabetic cataract or prevent it from getting worse.

 

Keywords

Type 1 diabetes mellitus Acute diabetic cataract Visual acuity Children

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