Iranian Journal of Pediatrics

Published by: Kowsar

A Nine-Year-Old Girl With Left Ventricle Non-Compaction and Skin Lesions (Carvajal Syndrome)

Behzad Mohammadpour Ahranjani 1 , * , Poria Moradi 2 , Shadab Nazari 3 and Sareh Farshadfar 3
Authors Information
1 Department of Pediatric Cardiology, Bahrami Hospital, Tehran University of Medical Sciences, Tehran, IR Iran
2 Songhor Health Center, Kermanshah University of Medical Sciences, Kermanshah, IR Iran
3 Kermanshah University of Medical Sciences, Kermanshah, IR Iran
Article information
  • Iranian Journal of Pediatrics: August 28, 2015, 25 (4); e370
  • Published Online: August 24, 2015
  • Article Type: Case Report
  • Received: September 5, 2014
  • Accepted: November 17, 2014
  • DOI: 10.5812/ijp.370

To Cite: Mohammadpour Ahranjani B, Moradi P, Nazari S, Farshadfar S. A Nine-Year-Old Girl With Left Ventricle Non-Compaction and Skin Lesions (Carvajal Syndrome), Iran J Pediatr. 2015 ; 25(4):e370. doi: 10.5812/ijp.370.

Copyright © 2015, Growth & Development Research Center.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
  • 1. Corrado D, Thiene G. Arrhythmogenic right ventricular cardiomyopathy/dysplasia: clinical impact of molecular genetic studies. Circulation. 2006; 113(13): 1634-7[DOI][PubMed]
  • 2. Bonow RO, Mann DL, Zipes DP, Libby P. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 2011;
  • 3. Protonotarios N, Tsatsopoulou A. Naxos disease and Carvajal syndrome: cardiocutaneous disorders that highlight the pathogenesis and broaden the spectrum of arrhythmogenic right ventricular cardiomyopathy. Cardiovasc Pathol. 2004; 13(4): 185-94[DOI][PubMed]
  • 4. Kilic T, Babaoglu K, Aygun F, Vural A, Ural D, Agacdiken A, et al. Biventricular involvement in a Turkish boy with palmoplantar hyperkeratosis and curly hair, an unusual presentation of Naxos-Carvajal syndrome. Int J Cardiol. 2007; 115(3)-5[DOI][PubMed]
  • 5. Prompona M, Kozlik-Feldmann R. Images in cardiovascular medicine. Circulation. 2007; 116(1): 2235
  • 6. Protonotarios N, Tsatsopoulou A. Naxos disease: cardiocutaneous syndrome due to cell adhesion defect. Orphanet J Rare Dis. 2006; 1: 4[DOI][PubMed]
  • 7. Kaplan SR, Gard JJ, Carvajal-Huerta L, Ruiz-Cabezas JC, Thiene G, Saffitz JE. Structural and molecular pathology of the heart in Carvajal syndrome. Cardiovasc Pathol. 2004; 13(1): 26-32[DOI][PubMed]
  • 8. Manolio TA, Baughman KL, Rodeheffer R, Pearson TA, Bristow JD, Michels VV, et al. Prevalence and etiology of idiopathic dilated cardiomyopathy (summary of a National Heart, Lung, and Blood Institute workshop. Am J Cardiol. 1992; 69(17): 1458-66[PubMed]
  • 9. Dec GW, Fuster V. Idiopathic dilated cardiomyopathy. N Engl J Med. 1994; 331(23): 1564-75[DOI][PubMed]
  • 10. Schwartz ML, Cox GF, Lin AE, Korson MS, Perez-Atayde A, Lacro RV, et al. Clinical approach to genetic cardiomyopathy in children. Circulation. 1996; 94(8): 2021-38[PubMed]
  • 11. Lipshultz SE, Sleeper LA, Towbin JA, Lowe AM, Orav EJ, Cox GF, et al. The incidence of pediatric cardiomyopathy in two regions of the United States. N Engl J Med. 2003; 348(17): 1647-55[DOI][PubMed]
  • 12. Nugent AW, Daubeney PE, Chondros P, Carlin JB, Cheung M, Wilkinson LC, et al. The epidemiology of childhood cardiomyopathy in Australia. N Engl J Med. 2003; 348(17): 1639-46[DOI][PubMed]
  • 13. Michels VV, Moll PP, Miller FA, Tajik AJ, Chu JS, Driscoll DJ, et al. The frequency of familial dilated cardiomyopathy in a series of patients with idiopathic dilated cardiomyopathy. N Engl J Med. 1992; 326(2): 77-82[DOI][PubMed]
  • 14. Weiford BC, Subbarao VD, Mulhern KM. Noncompaction of the ventricular myocardium. Circulation. 2004; 109(24): 2965-71[DOI][PubMed]
  • 15. Colan SD. Classification of the cardiomyopathies. Progr Pediatr Cardiol. 2007; 23(1–2): 5-15
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments