A Comparative Study of Risperidone and Aripiprazole in Attention Deficit Hyperactivity Disorder in Children Under Six Years Old: A Randomized Double-Blind Study
To Cite:
Razjouyan
K, Danesh
A, Khademi
M, Davari-Ashtiani
R, Noorbakhsh
S. A Comparative Study of Risperidone and Aripiprazole in Attention Deficit Hyperactivity Disorder in Children Under Six Years Old: A Randomized Double-Blind Study,
Iran J Pediatr.
2018
; 28(1):e60087.
doi: 10.5812/ijp.60087.
1.
Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry. 2007;164(6):942-8. doi: 10.1176/ajp.2007.164.6.942. [PubMed: 17541055].
2.
Wigal T, Greenhill L, Chuang S, McGough J, Vitiello B, Skrobala A, et al. Safety and tolerability of methylphenidate in preschool children with ADHD. J Am Acad Child Adolesc Psychiatry. 2006;45(11):1294-303. doi: 10.1097/01.chi.0000235082.63156.27. [PubMed: 17028508].
3.
Arabgol F, Panaghi L, Nikzad V. Risperidone Versus Methylphenidate in Treatment of Preschool Children With Attention-Deficit Hyperactivity Disorder. Iran J Pediatr. 2015;25(1). e265. doi: 10.5812/ijp.265. [PubMed: 26199694].
4.
Seida JC, Schouten JR, Mousavi SS, Hamm M, Beaith A, Vandermeer B, et al. AHRQ Comparative Effectiveness Reviews. First- and Second-Generation Antipsychotics for Children and Young Adults. Rockville (MD); 2012.
5.
Pathak P, West D, Martin BC, Helm ME, Henderson C. Evidence-based use of second-generation antipsychotics in a state Medicaid pediatric population, 2001-2005. Psychiatr Serv. 2010;61(2):123-9. doi: 10.1176/ps.2010.61.2.123. [PubMed: 20123816].
6.
Cooper WO, Arbogast PG, Ding H, Hickson GB, Fuchs DC, Ray WA. Trends in prescribing of antipsychotic medications for US children. Ambul Pediatr. 2006;6(2):79-83. doi: 10.1016/j.ambp.2005.11.002. [PubMed: 16530143].
7.
Gunther T, Herpertz-Dahlmann B, Jolles J, Konrad K. The influence of risperidone on attentional functions in children and adolescents with attention-deficit/hyperactivity disorder and co-morbid disruptive behavior disorder. J Child Adolesc Psychopharmacol. 2006;16(6):725-35. doi: 10.1089/cap.2006.16.725. [PubMed: 17201616].
8.
Pringsheim T, Gorman D. Second-generation antipsychotics for the treatment of disruptive behaviour disorders in children: a systematic review. Can J Psychiatry. 2012;57(12):722-7. doi: 10.1177/070674371205701203. [PubMed: 23228230].
9.
Burris KD, Molski TF, Xu C, Ryan E, Tottori K, Kikuchi T, et al. Aripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptors. J Pharmacol Exp Ther. 2002;302(1):381-9. [PubMed: 12065741].
10.
Matsushita M, Egashira N, Harada S, Okuno R, Mishima K, Iwasaki K, et al. Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder. J Pharmacol Sci. 2005;99(2):154-9. [PubMed: 16210777].
11.
Gao K, Muzina D, Gajwani P, Calabrese JR. Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a review. J Clin Psychiatry. 2006;67(9):1327-40. [PubMed: 17017818].
12.
Greenaway M, Elbe D. Focus on aripiprazole: a review of its use in child and adolescent psychiatry. J Canad Acad Child Adol Psychiatry. 2009;18(3):250.
13.
APA . Diagnostic criteria from dsm-iv-tr. American Psychiatric Pub; 2000.
14.
Pappas D. ADHD Rating Scale-IV: Checklists, Norms, and Clinical Interpretation. J Psychoeduc Assess. 2016;24(2):172-8. doi: 10.1177/0734282905285792.
15.
Sadock BJ, Sadock VA. Kaplan and Sadock's synopsis of psychiatry: Behavioral sciences/clinical psychiatry. Lippincott Williams & Wilkins; 2011.
16.
Bird HR, Canino G, Rubio-Stipec M, Ribera JC. Further measures of the psychometric properties of the Children's Global Assessment Scale. Arch Gen Psychiatry. 1987;44(9):821-4. [PubMed: 3632256].
17.
Shaffer D, Gould MS, Brasic J, Ambrosini P, Fisher P, Bird H, et al. A children's global assessment scale (CGAS). Arch Gen Psychiatry. 1983;40(11):1228-31. [PubMed: 6639293].
18.
Owen R, Sikich L, Marcus RN, Corey-Lisle P, Manos G, McQuade RD, et al. Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder. Pediatrics. 2009;124(6):1533-40. doi: 10.1542/peds.2008-3782. [PubMed: 19948625].
19.
Masi G, Gagliano A, Siracusano R, Berloffa S, Calarese T, Ilardo G, et al. Aripiprazole in children with Tourette's disorder and co-morbid attention-deficit/hyperactivity disorder: a 12-week, open-label, preliminary study. J Child Adolesc Psychopharmacol. 2012;22(2):120-5. doi: 10.1089/cap.2011.0081. [PubMed: 22375853].
20.
Findling RL, Short EJ, Leskovec T, Townsend LD, Demeter CA, McNamara NK, et al. Aripiprazole in children with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2008;18(4):347-54. doi: 10.1089/cap.2007.0124. [PubMed: 18759644].
21.
Correia Filho AG, Bodanese R, Silva TL, Alvares JP, Aman M, Rohde LA. Comparison of risperidone and methylphenidate for reducing ADHD symptoms in children and adolescents with moderate mental retardation. J Am Acad Child Adolesc Psychiatry. 2005;44(8):748-55. doi: 10.1097/01.chi.0000166986.30592.67. [PubMed: 16034276].
Readers' Comments