Iranian Journal of Pediatrics

Published by: Kowsar

The Relationship Between Early Weight Z-Score Changes and Nutritional Differences in Very Low Birth Weight Infants During Hospital Stay

Chu-yi Guo 1 , Mu-xue Yu 1 , * , Lin-xia Deng 1 , Wang-kai Liu 1 and Si-qi Zhuang 1
Authors Information
1 Department of Pediatrics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
Article information
  • Iranian Journal of Pediatrics: August 2018, 28 (4); e62520
  • Published Online: June 10, 2018
  • Article Type: Research Article
  • Received: October 6, 2017
  • Revised: January 19, 2018
  • Accepted: March 11, 2018
  • DOI: 10.5812/ijp.62520

To Cite: Guo C, Yu M, Deng L, Liu W, Zhuang S. The Relationship Between Early Weight Z-Score Changes and Nutritional Differences in Very Low Birth Weight Infants During Hospital Stay, Iran J Pediatr. 2018 ; 28(4):e62520. doi: 10.5812/ijp.62520.

Copyright © 2018, Iranian Journal of Pediatrics. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Background
2. Methods
3. Results
4. Discussion
  • 1. Fanaro S. Feeding intolerance in the preterm infant. Early Hum Dev. 2013;89 Suppl 2:S13-20. doi: 10.1016/j.earlhumdev.2013.07.013. [PubMed: 23962482].
  • 2. Koletzko B, Uauy R. Nutritional care of preterm infants. Switzerland: Karger; 2014.
  • 3. Ehrenkranz RA, Younes N, Lemons JA, Fanaroff AA, Donovan EF, Wright LL, et al. Longitudinal growth of hospitalized very low birth weight infants. Pediatrics. 1999;104(2 Pt 1):280-9. [PubMed: 10429008].
  • 4. Horbar JD, Ehrenkranz RA, Badger GJ, Edwards EM, Morrow KA, Soll RF, et al. Weight Growth Velocity and Postnatal Growth Failure in Infants 501 to 1500 Grams: 2000-2013. Pediatrics. 2015;136(1):e84-92. doi: 10.1542/peds.2015-0129. [PubMed: 26101360].
  • 5. Olsen IE, Harris CL, Lawson ML, Berseth CL. Higher protein intake improves length, not weight, z scores in preterm infants. J Pediatr Gastroenterol Nutr. 2014;58(4):409-16. doi: 10.1097/MPG.0000000000000237. [PubMed: 24231639].
  • 6. Ong KK, Ahmed ML, Emmett PM, Preece MA, Dunger DB. Association between postnatal catch-up growth and obesity in childhood: prospective cohort study. BMJ. 2000;320(7240):967-71. [PubMed: 10753147]. [PubMed Central: PMC27335].
  • 7. Collaborative Group for the Nutritional G, Developmental Study on Very Low Birth Weight I. [Postnatal growth of very low birth weight infants during hospitalization]. Zhonghua Er Ke Za Zhi. 2013;51(1):4-11. [PubMed: 23527924].
  • 8. Fenton TR, Kim JH. A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatr. 2013;13:59. doi: 10.1186/1471-2431-13-59. [PubMed: 23601190]. [PubMed Central: PMC3637477].
  • 9. Lapillonne A. Enteral and parenteral lipid requirements of preterm infants. World Rev Nutr Diet. 2014;110:82-98. doi: 10.1159/000358460. [PubMed: 24751623].
  • 10. Salama GS, Kaabneh MA, Almasaeed MN, Alquran M. Intravenous lipids for preterm infants: a review. Clin Med Insights Pediatr. 2015;9:25-36. doi: 10.4137/CMPed.S21161. [PubMed: 25698888]. [PubMed Central: PMC4325703].
  • 11. Drenckpohl D, McConnell C, Gaffney S, Niehaus M, Macwan KS. Randomized trial of very low birth weight infants receiving higher rates of infusion of intravenous fat emulsions during the first week of life. Pediatrics. 2008;122(4):743-51. doi: 10.1542/peds.2007-2282. [PubMed: 18829797].
  • 12. Vlaardingerbroek H, Vermeulen MJ, Carnielli VP, Vaz FM, van den Akker CH, van Goudoever JB. Growth and fatty acid profiles of VLBW infants receiving a multicomponent lipid emulsion from birth. J Pediatr Gastroenterol Nutr. 2014;58(4):417-27. doi: 10.1097/MPG.0000000000000280. [PubMed: 24667866].
  • 13. dit Trolli SE, Kermorvant-Duchemin E, Huon C, Bremond-Gignac D, Lapillonne A. Early lipid supply and neurological development at one year in very low birth weight (VLBW) preterm infants. Early Hum Dev. 2012;88 Suppl 1:S25-9. doi: 10.1016/j.earlhumdev.2011.12.024. [PubMed: 22264437].
  • 14. Morgan C, McGowan P, Herwitker S, Hart AE, Turner MA. Postnatal head growth in preterm infants: a randomized controlled parenteral nutrition study. Pediatrics. 2014;133(1):e120-8. doi: 10.1542/peds.2013-2207. [PubMed: 24379229].
  • 15. Herrmann KR, Herrmann KR. Early parenteral nutrition and successful postnatal growth of premature infants. Nutr Clin Pract. 2010;25(1):69-75. doi: 10.1177/0884533609359001. [PubMed: 20130159].
  • 16. Rouwet EV, Heineman E, Buurman WA, ter Riet G, Ramsay G, Blanco CE. Intestinal permeability and carrier-mediated monosaccharide absorption in preterm neonates during the early postnatal period. Pediatr Res. 2002;51(1):64-70. doi: 10.1203/00006450-200201000-00012. [PubMed: 11756641].
  • 17. Flidel-Rimon O, Friedman S, Lev E, Juster-Reicher A, Amitay M, Shinwell ES. Early enteral feeding and nosocomial sepsis in very low birthweight infants. Arch Dis Child Fetal Neonatal Ed. 2004;89(4):F289-92. doi: 10.1136/adc.2002.021923. [PubMed: 15210657]. [PubMed Central: PMC1721698].
  • 18. Moltu SJ, Blakstad EW, Strommen K, Almaas AN, Nakstad B, Ronnestad A, et al. Enhanced feeding and diminished postnatal growth failure in very-low-birth-weight infants. J Pediatr Gastroenterol Nutr. 2014;58(3):344-51. doi: 10.1097/MPG.0000000000000220. [PubMed: 24556755]. [PubMed Central: PMC3940525].
  • 19. Leaf A, Dorling J, Kempley S, McCormick K, Mannix P, Linsell L, et al. Early or delayed enteral feeding for preterm growth-restricted infants: a randomized trial. Pediatrics. 2012;129(5):e1260-8. doi: 10.1542/peds.2011-2379. [PubMed: 22492770].
  • 20. Morgan J, Young L, McGuire W. Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants. Cochrane Database Syst Rev. 2015;(10). CD001241. doi: 10.1002/14651858.CD001241.pub6. [PubMed: 26469124].
  • 21. Dutta S, Singh B, Chessell L, Wilson J, Janes M, McDonald K, et al. Guidelines for feeding very low birth weight infants. Nutrients. 2015;7(1):423-42. doi: 10.3390/nu7010423. [PubMed: 25580815]. [PubMed Central: PMC4303848].
  • 22. Maggio L, Cota F, Gallini F, Lauriola V, Zecca C, Romagnoli C. Effects of high versus standard early protein intake on growth of extremely low birth weight infants. J Pediatr Gastroenterol Nutr. 2007;44(1):124-9. doi: 10.1097/01.mpg.0000237927.00105.f7. [PubMed: 17204965].
  • 23. Agostoni C, Buonocore G, Carnielli VP, De Curtis M, Darmaun D, Decsi T, et al. Enteral nutrient supply for preterm infants: commentary from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2010;50(1):85-91. doi: 10.1097/MPG.0b013e3181adaee0. [PubMed: 19881390].
  • 24. Hay WW. Early postnatal nutritional requirements of the very preterm infant based on a presentation at the NICHD-AAP workshop on research in neonatology. J Perinatol. 2006;26 Suppl 2:S13-8. doi: 10.1038/ [PubMed: 16801962].
  • 25. Stephens BE, Walden RV, Gargus RA, Tucker R, McKinley L, Mance M, et al. First-week protein and energy intakes are associated with 18-month developmental outcomes in extremely low birth weight infants. Pediatrics. 2009;123(5):1337-43. doi: 10.1542/peds.2008-0211. [PubMed: 19403500].
  • 26. Shlomai NO, Patole S. Nutrition in Preterm Infants with bronchopulmonary dysplasia. Nutrition for the Preterm Neonate. Springer; 2013.
  • 27. Uberos J, Lardon-Fernandez M, Machado-Casas I, Molina-Oya M, Narbona-Lopez E. Nutrition in extremely low birth weight infants: impact on bronchopulmonary dysplasia. Minerva Pediatr. 2016;68(6):419-26. [PubMed: 25407225].
  • 28. Gianni ML, Roggero P, Colnaghi MR, Piemontese P, Amato O, Orsi A, et al. The role of nutrition in promoting growth in pre-term infants with bronchopulmonary dysplasia: a prospective non-randomised interventional cohort study. BMC Pediatr. 2014;14:235. doi: 10.1186/1471-2431-14-235. [PubMed: 25241811]. [PubMed Central: PMC4177697].
  • 29. Frank L, Sosenko IR. Undernutrition as a major contributing factor in the pathogenesis of bronchopulmonary dysplasia. Am Rev Respir Dis. 1988;138(3):725-9. doi: 10.1164/ajrccm/138.3.725. [PubMed: 3059876].
  • 30. Prince A, Groh-Wargo S. Nutrition management for the promotion of growth in very low birth weight premature infants. Nutr Clin Pract. 2013;28(6):659-68. doi: 10.1177/0884533613506752. [PubMed: 24163320].
  • 31. Hsieh MH, Pai W, Tseng HI, Yang SN, Lu CC, Chen HL. Parenteral nutrition-associated cholestasis in premature babies: risk factors and predictors. Pediatr Neonatol. 2009;50(5):202-7. doi: 10.1016/S1875-9572(09)60064-4. [PubMed: 19856863].
  • 32. Robinson DT, Ehrenkranz RA. Parenteral nutrition-associated cholestasis in small for gestational age infants. J Pediatr. 2008;152(1):59-62. doi: 10.1016/j.jpeds.2007.06.002. [PubMed: 18154901].
  • 33. Burrin DG, Ng K, Stoll B, Saenz De Pipaon M. Impact of new-generation lipid emulsions on cellular mechanisms of parenteral nutrition-associated liver disease. Adv Nutr. 2014;5(1):82-91. doi: 10.3945/an.113.004796. [PubMed: 24425726]. [PubMed Central: PMC3884104].
  • 34. Yan W, Hong L, Wang Y, Feng Y, Lu L, Tao Y, et al. Retrospective Dual-Center Study of Parenteral Nutrition-Associated Cholestasis in Premature Neonates: 15 Years' Experience. Nutr Clin Pract. 2017;32(3):407-13. doi: 10.1177/0884533616687532. [PubMed: 28135431].
  • 35. Repa A, Lochmann R, Unterasinger L, Weber M, Berger A, Haiden N. Aggressive nutrition in extremely low birth weight infants: impact on parenteral nutrition associated cholestasis and growth. PeerJ. 2016;4. e2483. doi: 10.7717/peerj.2483. [PubMed: 27688976]. [PubMed Central: PMC5036079].
  • 36. Ehrenkranz RA. Early, aggressive nutritional management for very low birth weight infants: what is the evidence? Semin Perinatol. 2007;31(2):48-55. doi: 10.1053/j.semperi.2007.02.001. [PubMed: 17462488].
  • 37. Ehrenkranz RA. Ongoing issues in the intensive care for the periviable infant--nutritional management and prevention of bronchopulmonary dysplasia and nosocomial infections. Semin Perinatol. 2014;38(1):25-30. doi: 10.1053/j.semperi.2013.07.005. [PubMed: 24468566].
  • 38. Hamilton E, Massey C, Ross J, Taylor S. Early enteral feeding in very low birth weight infants. Early Hum Dev. 2014;90(5):227-30. doi: 10.1016/j.earlhumdev.2014.02.005. [PubMed: 24612934].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments