Iranian Journal of Pediatrics

Published by: Kowsar

Comparative Analysis of Local CDC and IOTF Criteria for Detecting Cardiovascular Risk Factors in Children from Tehran

Maryam Barzin 1 , Sahar Ghareh 2 , * , Sorena Keihani 1 , Sara Serahati 1 , Majid Valizadeh 1 and Fereidoun Azizi 3
Authors Information
1 Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Mashhad Medical Branch, Faculty of Medicine, Islamic Azad University, Mashhad, Iran
Article information
  • Iranian Journal of Pediatrics: October 2018, 28 (5); e65209
  • Published Online: August 12, 2018
  • Article Type: Research Article
  • Received: December 30, 2017
  • Revised: March 5, 2018
  • Accepted: May 15, 2018
  • DOI: 10.5812/ijp.65209

To Cite: Barzin M, Ghareh S, Keihani S, Serahati S, Valizadeh M, et al. Comparative Analysis of Local CDC and IOTF Criteria for Detecting Cardiovascular Risk Factors in Children from Tehran, Iran J Pediatr. 2018 ; 28(5):e65209. doi: 10.5812/ijp.65209.

Copyright © 2018, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Wang Y, Lobstein T. Worldwide trends in childhood overweight and obesity. Int J Pediatr Obes. 2006;1(1):11-25. doi: 10.1080/17477160600586747.
  • 2. Maziak W, Ward KD, Stockton MB. Childhood obesity: are we missing the big picture? Obes Rev. 2008;9(1):35-42.
  • 3. Ebbeling CB, Pawlak DB, Ludwig DS. Childhood obesity: public-health crisis, common sense cure. Lancet. 2002;360(9331):473-82. doi: 10.1016/S0140-6736(02)09678-2. [PubMed: 12241736].
  • 4. Friedemann C, Heneghan C, Mahtani K, Thompson M, Perera R, Ward AM. Cardiovascular disease risk in healthy children and its association with body mass index: systematic review and meta-analysis. BMJ. 2012;345. e4759. doi: 10.1136/bmj.e4759. [PubMed: 23015032]. [PubMed Central: PMC3458230].
  • 5. O'Malley G, Santoro N, Northrup V, D'Adamo E, Shaw M, Eldrich S, et al. High normal fasting glucose level in obese youth: a marker for insulin resistance and beta cell dysregulation. Diabetologia. 2010;53(6):1199-209. doi: 10.1007/s00125-010-1693-0. [PubMed: 20204321].
  • 6. Biro FM, Wien M. Childhood obesity and adult morbidities. Am J Clin Nutr. 2010;91(5):1499S-505S. doi: 10.3945/ajcn.2010.28701B.
  • 7. Franks PW, Hanson RL, Knowler WC, Sievers ML, Bennett PH, Looker HC. Childhood obesity, other cardiovascular risk factors, and premature death. N Engl J Med. 2010;362(6):485-93. doi: 10.1056/NEJMoa0904130.
  • 8. Reilly JJ. Assessment of childhood obesity: national reference data or international approach? Obes Res. 2002;10(8):838-40. doi: 10.1038/oby.2002.113.
  • 9. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320(7244):1240-3. [PubMed: 10797032]. [PubMed Central: PMC27365].
  • 10. Flegal KM, Ogden CL. Childhood obesity: are we all speaking the same language? Adv Nutr. 2011;2(2):159S-66S. doi: 10.3945/an.111.000307. [PubMed: 22332047]. [PubMed Central: PMC3065752].
  • 11. World Health Organization. WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. Geneva: World Health Organization; 2006.
  • 12. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, et al. CDC growth charts: United States. Adv Data. 2000;(314):1-27. [PubMed: 11183293].
  • 13. Chinn S. Definitions of childhood obesity: current practice. Eur J Clin Nutr. 2006;60(10):1189-94. doi: 10.1038/sj.ejcn.1602436. [PubMed: 16639415].
  • 14. Shields M, Tremblay MS. Canadian childhood obesity estimates based on WHO, IOTF and CDC cut-points. Int J Pediatr Obes. 2010;5(3):265-73. doi: 10.3109/17477160903268282. [PubMed: 20210678].
  • 15. Kelishadi R, Ardalan G, Gheiratmand R, Majdzadeh R, Hosseini M, Gouya MM, et al. Thinness, overweight and obesity in a national sample of Iranian children and adolescents: CASPIAN Study. Child Care Health Dev. 2008;34(1):44-54. doi: 10.1111/j.1365-2214.2007.00744.x. [PubMed: 18171443].
  • 16. Ghanbari S, Ayatollahi SM. Comparing the role of standard references on the prevalence of Iranian children and adolescents' overweight and obesity: A systematic review and meta-analysis. J Res Med Sci. 2016;21:121. doi: 10.4103/1735-1995.193512. [PubMed: 28331507]. [PubMed Central: PMC5348832].
  • 17. Martinez-Costa C, Nunez F, Montal A, Brines J. Relationship between childhood obesity cut-offs and metabolic and vascular comorbidities: comparative analysis of three growth standards. J Hum Nutr Diet. 2014;27 Suppl 2:75-83. doi: 10.1111/jhn.12140. [PubMed: 23808870].
  • 18. Freedman DS, Fulton JE, Dietz WH, Pan L, Nihiser AJ, Srinivasan SR, et al. The identification of children with adverse risk factor levels by body mass index cutoffs from 2 classification systems: the Bogalusa Heart Study. Am J Clin Nutr. 2010;92(6):1298-305. doi: 10.3945/ajcn.2010.29758. [PubMed: 20980492]. [PubMed Central: PMC2980956].
  • 19. Kakinami L, Henderson M, Delvin EE, Levy E, O'Loughlin J, Lambert M, et al. Association between different growth curve definitions of overweight and obesity and cardiometabolic risk in children. CMAJ. 2012;184(10):E539-50. doi: 10.1503/cmaj.110797. [PubMed: 22546882]. [PubMed Central: PMC3394848].
  • 20. Valerio G, Balsamo A, Baroni MG, Brufani C, Forziato C, Grugni G, et al. Childhood obesity classification systems and cardiometabolic risk factors: a comparison of the Italian, World Health Organization and International Obesity Task Force references. Ital J Pediatr. 2017;43(1):19. doi: 10.1186/s13052-017-0338-z. [PubMed: 28257654]. [PubMed Central: PMC5347828].
  • 21. Azizi F, Ghanbarian A, Momenan AA, Hadaegh F, Mirmiran P, Hedayati M, et al. Prevention of non-communicable disease in a population in nutrition transition: Tehran Lipid and Glucose Study phase II. Trials. 2009;10:5. doi: 10.1186/1745-6215-10-5. [PubMed: 19166627]. [PubMed Central: PMC2656492].
  • 22. Cole TJ, Green PJ. Smoothing reference centile curves: the LMS method and penalized likelihood. Stat Med. 1992;11(10):1305-19. [PubMed: 1518992].
  • 23. Chinn S, Rona RJ. International definitions of overweight and obesity for children: a lasting solution? Ann Hum Biol. 2002;29(3):306-13. doi: 10.1080/03014460110085340. [PubMed: 12031139].
  • 24. Speiser PW, Rudolf MCJ, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, et al. Childhood obesity. J Clin Endocr Metab. 2005;90(3):1871-87. doi: 10.1210/jc.2004-1389.
  • 25. Cole TJ, Lobstein T. Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity. Pediatr Obes. 2012;7(4):284-94. doi: 10.1111/j.2047-6310.2012.00064.x. [PubMed: 22715120].
  • 26. Moyer VA, Klein JD, Ockene JK, Teutsch SM, Johnson MS, Allan JD, et al. Screening for overweight in children and adolescents: where is the evidence? a commentary by the childhood obesity working group of the US Preventive Services Task Force. Pediatrics. 2005;116(1):235-8. doi: 10.1542/peds.2005-0305. [PubMed: 15995061].
  • 27. Reilly JJ, Methven E, McDowell ZC, Hacking B, Alexander D, Stewart L, et al. Health consequences of obesity. Arch Dis Child. 2003;88(9):748-52. [PubMed: 12937090]. [PubMed Central: PMC1719633].
  • 28. Hosseinpanah F, Asghari G, Barzin M, Ghareh S, Azizi F. Adolescence metabolic syndrome or adiposity and early adult metabolic syndrome. J Pediatr. 2013;163(6):1663-9. doi: 10.1016/j.jpeds.2013.07.032.
  • 29. Reilly JJ, Kelly J. Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review. Int J Obes (Lond). 2011;35(7):891-8. doi: 10.1038/ijo.2010.222. [PubMed: 20975725].
  • 30. Singh AS, Mulder C, Twisk JW, van Mechelen W, Chinapaw MJ. Tracking of childhood overweight into adulthood: a systematic review of the literature. Obes Rev. 2008;9(5):474-88. doi: 10.1111/j.1467-789X.2008.00475.x. [PubMed: 18331423].

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