IF: 0.587
Cite Score:
0.7
THOMSON REUTERS - SCOPUS

Treatment of Cutaneous Injuries of Neonates Induced by Drug Extravasation with Hyaluronidase and Hirudoid

AUTHORS

Ya-Min Yan 1 , Qiao-Ling Fan 2 , Ai-Qiu Li 3 , Jia-Ling Chen 4 , Fei-Fei Dong 5 , Mei Gong 6 , *

How to Cite: Yan Y, Fan Q, Li A, Chen J, Dong F, et al. Treatment of Cutaneous Injuries of Neonates Induced by Drug Extravasation with Hyaluronidase and Hirudoid, Iran J Pediatr. 2014 ; 24(4):345-351.

ARTICLE INFORMATION

Iranian Journal of Pediatrics: 24 (4); 345-351
Published Online: July 03, 2014
Article Type: Research Article
Received: July 04, 2013
Accepted: May 14, 2014

Crossmark

CHEKING

READ FULL TEXT
Abstract

Objective: To analyze the effects of hyaluronidase and hirudoid treatment on drug extravasation in neonates.Methods: The medical records of 13 neonates with drug extravasation treated with hyaluronidase and hirudoid between August 1st, 2010 and May 1st, 2012 were analyzed retrospectively. The treatment procedure for drug extravasation adhered to the protocol in neonatal department. The information including age, sex, weight, diagnosis, size of affected area, site of extravasation and treatment was collected.Findings: The extravasation injuries alleviated and the symptoms improved after treatment, no adverse drug effects were reported with use of hyaluronidase and hirudoid.Conclusion: The treatment appeared to be beneficial in the management of extravasations of various medications in neonates and may be useful in reducing the severity of cutaneous toxicosis. However, further studies with large samples are still needed to assess the effectiveness and safety of hyaluronidase and hirudoid.

 

Keywords

Treatment Drug Extravasation Hyaluronidase Hirudoid Neonate

© 0, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

Fulltext

References

  • 1.

    References are available on the PDF.

  • COMMENTS

    LEAVE A COMMENT HERE: