Iranian Journal of Pediatrics

Published by: Kowsar

Prolonged Fever and Intravenous Immunoglobulin Resistance in Kawasaki Disease: Should Macrophage Activation Syndrome Be Considered?

Mahdieh Sadat Mousavi 1 , Raheleh Assari 1 , 2 , Fatemeh Tahghighi 1 , 3 , Hamid Eshaghi 1 , 3 and Vahid Ziaee 1 , 2 , 3 , *
Authors Information
1 Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
2 Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
3 Children's Medical Center, Pediatric Center of Excellence, Tehran, Iran
Article information
  • Iranian Journal of Pediatrics: 29 (1); e69170
  • Published Online: February 19, 2019
  • Article Type: Case Report
  • Received: April 7, 2018
  • Revised: October 9, 2018
  • Accepted: October 13, 2018
  • DOI: 10.5812/ijp.69170

To Cite: Mousavi M S, Assari R , Tahghighi F, Eshaghi H, Ziaee V. Prolonged Fever and Intravenous Immunoglobulin Resistance in Kawasaki Disease: Should Macrophage Activation Syndrome Be Considered?, Iran J Pediatr. Online ahead of Print ; 29(1):e69170. doi: 10.5812/ijp.69170.

Abstract
Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
Acknowledgements
Footnotes
References
  • 1. Ravelli A, Magni-Manzoni S, Pistorio A, Besana C, Foti T, Ruperto N, et al. Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. J Pediatr. 2005;146(5):598-604. doi: 10.1016/j.jpeds.2004.12.016. [PubMed: 15870661].
  • 2. Lin CI, Yu HH, Lee JH, Wang LC, Lin YT, Yang YH, et al. Clinical analysis of macrophage activation syndrome in pediatric patients with autoimmune diseases. Clin Rheumatol. 2012;31(8):1223-30. doi: 10.1007/s10067-012-1998-0. [PubMed: 22615046].
  • 3. Moradinejad MH, Ziaee V. The incidence of macrophage activation syndrome in children with rheumatic disorders. Minerva Pediatr. 2011;63(6):459-66. [PubMed: 22075800].
  • 4. Filipovich AH. Hemophagocytic lymphohistiocytosis (HLH) and related disorders. Hematology Am Soc Hematol Educ Program. 2009:127-31. doi: 10.1182/asheducation-2009.1.127. [PubMed: 20008190].
  • 5. Latino GA, Manlhiot C, Yeung RS, Chahal N, McCrindle BW. Macrophage activation syndrome in the acute phase of Kawasaki disease. J Pediatr Hematol Oncol. 2010;32(7):527-31. doi: 10.1097/MPH.0b013e3181dccbf4. [PubMed: 20485197].
  • 6. Ayusawa M, Sonobe T, Uemura S, Ogawa S, Nakamura Y, Kiyosawa N, et al. Revision of diagnostic guidelines for Kawasaki disease (the 5th revised edition). Pediatr Int. 2005;47(2):232-4. doi: 10.1111/j.1442-200x.2005.02033.x. [PubMed: 15771703].
  • 7. Wang W, Gong F, Zhu W, Fu S, Zhang Q. Macrophage activation syndrome in Kawasaki disease: More common than we thought? Semin Arthritis Rheum. 2015;44(4):405-10. doi: 10.1016/j.semarthrit.2014.07.007. [PubMed: 25200945].
  • 8. Garcia-Pavon S, Yamazaki-Nakashimada MA, Baez M, Borjas-Aguilar KL, Murata C. Kawasaki disease complicated with macrophage activation syndrome: A systematic review. J Pediatr Hematol Oncol. 2017;39(6):445-51. doi: 10.1097/MPH.0000000000000872. [PubMed: 28562511].
  • 9. Assari R, Ziaee V, Mirmohammadsadeghi A, Moradinejad MH. Dynamic changes, cut-off points, sensitivity, and specificity of laboratory data to differentiate macrophage activation syndrome from active disease. Dis Markers. 2015;2015:424381. doi: 10.1155/2015/424381. [PubMed: 26063955]. [PubMed Central: PMC4430633].
  • 10. Maric LS, Knezovic I, Papic N, Mise B, Roglic S, Markovinovic L, et al. Risk factors for coronary artery abnormalities in children with Kawasaki disease: A 10-year experience. Rheumatol Int. 2015;35(6):1053-8. doi: 10.1007/s00296-014-3186-9. [PubMed: 25429794].
  • 11. Muise A, Tallett SE, Silverman ED. Are children with Kawasaki disease and prolonged fever at risk for macrophage activation syndrome? Pediatrics. 2003;112(6 Pt 1). e495. [PubMed: 14654653].
  • 12. Su HC, Nguyen KB, Salazar-Mather TP, Ruzek MC, Dalod MY, Biron CA. NK cell functions restrain T cell responses during viral infections. Eur J Immunol. 2001;31(10):3048-55. doi: 10.1002/1521-4141(2001010)31:10<3048::AID-IMMU3048gt;3.0.CO;2-1. [PubMed: 11592081].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments