Iranian Journal of Pediatrics

Published by: Kowsar

Cord Blood Alkaline Phosphatase as an Indicator of Neonatal Jaundice

Mousa Ahmadpour-Kacho 1 , Yadollah Zahed Pasha 1 , Mohsen Haghshenas 1 , Zahra Akbarian Rad 1 , Alireza Firouzjahi 1 , Ali Bijani 1 , Abdollah Dehvari 2 , * and Mehrangiz Baleghi 1
Authors Information
1 Babol University of Medical Sciences, Babol, IR Iran
2 Children And Adolescent Health Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran
Article information
  • Iranian Journal of Pediatrics: October 28, 2015, 25 (5); e718
  • Published Online: October 6, 2015
  • Article Type: Research Article
  • Received: February 16, 2015
  • Accepted: July 29, 2015
  • DOI: 10.5812/ijp.718

To Cite: Ahmadpour-Kacho M, Zahed Pasha Y, Haghshenas M, Akbarian Rad Z, Firouzjahi A, et al. Cord Blood Alkaline Phosphatase as an Indicator of Neonatal Jaundice, Iran J Pediatr. 2015 ; 25(5):e718. doi: 10.5812/ijp.718.

Copyright © 2015, Growth & Development Research Center.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Sgro M, Campbell D, Shah V. Incidence and causes of severe neonatal hyperbilirubinemia in Canada. CMAJ. 2006; 175(6): 587-90[DOI][PubMed]
  • 2. Zeitoun AA, Elhagrasy HF, Abdelsatar DM. Predictive value of umbilical cord blood bilirubin in neonatal hyperbilirubinemia. Gaz Egypt Paediatr Assoc. 2013; 61(1): 23-30[DOI]
  • 3. Tan KL, Loganath A, Roy AC, Goh HH, Karim SM, Ratnam SS. Cord plasma alpha-fetoprotein values and neonatal jaundice. Pediatrics. 1984; 74(6): 1065-8[PubMed]
  • 4. Nalbantoglu A, Ovali F, Nalbantoglu B. Alkaline phosphatase as an early marker of hemolysis in newborns. Pediatr Int. 2011; 53(6): 936-8[DOI][PubMed]
  • 5. Tinnion RJ, Embleton ND. How to use... alkaline phosphatase in neonatology. Arch Dis Child Educ Pract Ed. 2012; 97(4): 157-63[DOI][PubMed]
  • 6. Monanu MO, Uwakwe AA, Onwubiko D. <italic>In vitro</italic> effects of sodium benzoate on the activities of aspartate and alanine amino transferases, and alkaline phosphatase from human erythrocytes of different genotypes. Biokemistri. 2005; 17(1): 33-8[DOI]
  • 7. Chou HC, Chien CT, Tsao PN, Hsieh WS, Chen CY, Chang MH. Prediction of severe neonatal hyperbilirubinemia using cord blood hydrogen peroxide: a prospective study. PLoS One. 2014; 9(1)[DOI][PubMed]
  • 8. Knupfer M, Pulzer F, Gebauer C, Robel-Tillig E, Vogtmann C. Predictive value of umbilical cord blood bilirubin for postnatal hyperbilirubinaemia. Acta Paediatr. 2005; 94(5): 581-7[DOI][PubMed]
  • 9. Okuyama H, Yonetani M, Uetani Y, Nakamura H. End-tidal carbon monoxide is predictive for neonatal non-hemolytic hyperbilirubinemia. Pediatr Int. 2001; 43(4): 329-33[PubMed]
  • 10. Alpay F, Sarici SU, Tosuncuk HD, Serdar MA, Inanc N, Gokcay E. The value of first-day bilirubin measurement in predicting the development of significant hyperbilirubinemia in healthy term newborns. Pediatrics. 2000; 106(2)[PubMed]
  • 11. Sarici SU, Yurdakok M, Serdar MA, Oran O, Erdem G, Tekinalp G, et al. An early (sixth-hour) serum bilirubin measurement is useful in predicting the development of significant hyperbilirubinemia and severe ABO hemolytic disease in a selective high-risk population of newborns with ABO incompatibility. Pediatrics. 2002; 109(4)[PubMed]
  • 12. Fenton TR, Lyon AW, Rose MS. Cord blood calcium, phosphate, magnesium, and alkaline phosphatase gestational age-specific reference intervals for preterm infants. BMC Pediatr. 2011; 11(1): 76[DOI]
  • 13. Abbasian M, Chaman R, Delvarian Zadeh M, Amiri M, Raei M, Norouzi P, et al. Investigating the prevalence of calcium deficiency and some of its influencing factors in pregnant women and their neonates [in Persian]. Knowledge Health . 2012; 7(1): 39-43
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments