Iranian Journal of Pediatrics

Published by: Kowsar

How Does Functional Constipation Affect Growth Status in Children?

Azizollah Yousefi 1 , Shima Mohamadian 2 , Parisa Morovati Sharifabadi 2 , Shahrbanoo Nakhaei 2 and Elahe Norouzi 3 , *
Authors Information
1 Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
2 Aliasghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran
3 Rasoul-e-Akram Medical Center, Iran University of Medical Sciences, Tehran, Iran
Article information
  • Iranian Journal of Pediatrics: 29 (2); e85700
  • Published Online: January 15, 2019
  • Article Type: Research Article
  • Received: October 23, 2018
  • Revised: December 12, 2018
  • Accepted: December 27, 2018
  • DOI: 10.5812/ijp.85700

To Cite: Yousefi A, Mohamadian S, Morovati Sharifabadi P, Nakhaei S, Norouzi E. How Does Functional Constipation Affect Growth Status in Children?, Iran J Pediatr. Online ahead of Print ; 29(2):e85700. doi: 10.5812/ijp.85700.

Copyright © 2019, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. van den Berg MM, Benninga MA, Di Lorenzo C. Epidemiology of childhood constipation: A systematic review. Am J Gastroenterol. 2006;101(10):2401-9. doi: 10.1111/j.1572-0241.2006.00771.x. [PubMed: 17032205].
  • 2. Tabbers MM, DiLorenzo C, Berger MY, Faure C, Langendam MW, Nurko S, et al. Evaluation and treatment of functional constipation in infants and children: Evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014;58(2):258-74. doi: 10.1097/MPG.0000000000000266. [PubMed: 24345831].
  • 3. Liem O, Harman J, Benninga M, Kelleher K, Mousa H, Di Lorenzo C. Health utilization and cost impact of childhood constipation in the United States. J Pediatr. 2009;154(2):258-62. doi: 10.1016/j.jpeds.2008.07.060. [PubMed: 18822430].
  • 4. Baker SS, Liptak GS, Colletti RB, Croffie JM, Di Lorenzo C, Ector W, et al. Constipation in infants and children: Evaluation and treatment. A medical position statement of the North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr. 1999;29(5):612-26. doi: 10.1097/00005176-199911000-00029. [PubMed: 10554136].
  • 5. Bardisa-Ezcurra L, Ullman R, Gordon J, Guideline Development G. Diagnosis and management of idiopathic childhood constipation: Summary of NICE guidance. BMJ. 2010;340:c2585. doi: 10.1136/bmj.c2585. [PubMed: 20516006].
  • 6. Tabbers MM, Boluyt N, Berger MY, Benninga MA. Clinical practice: Diagnosis and treatment of functional constipation. Eur J Pediatr. 2011;170(8):955-63. doi: 10.1007/s00431-011-1515-5. [PubMed: 21701812].
  • 7. North American Society for Pediatric Gastroenterology H; Nutrition. Evaluation and treatment of constipation in children: Summary of updated recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2006;43(3):405-7. doi: 10.1097/01.mpg.0000232574.41149.0a. [PubMed: 16954970].
  • 8. Felt B, Wise CG, Olson A, Kochhar P, Marcus S, Coran A. Guideline for the management of pediatric idiopathic constipation and soiling. Multidisciplinary team from the University of Michigan Medical Center in Ann Arbor. Arch Pediatr Adolesc Med. 1999;153(4):380-5. doi: 10.1001/archpedi.153.4.380. [PubMed: 10201721].
  • 9. Tabbers MM, Boluyt N, Berger MY, Benninga MA. Constipation in children. BMJ Clin Evid. 2010;2010. [PubMed: 21718570]. [PubMed Central: PMC2907595].
  • 10. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: An emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336(7650):924-6. doi: 10.1136/bmj.39489.470347.AD. [PubMed: 18436948]. [PubMed Central: PMC2335261].
  • 11. Levy EI, Lemmens R, Vandenplas Y, Devreker T. Functional constipation in children: Challenges and solutions. Pediatric Health Med Ther. 2017;8:19-27. doi: 10.2147/PHMT.S110940. [PubMed: 29388621]. [PubMed Central: PMC5774595].
  • 12. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130(5):1480-91. doi: 10.1053/j.gastro.2005.11.061. [PubMed: 16678561].
  • 13. Bekkali N, Hamers SL, Reitsma JB, Van Toledo L, Benninga MA. Infant stool form scale: Development and results. J Pediatr. 2009;154(4):521-526 e1. doi: 10.1016/j.jpeds.2008.10.010. [PubMed: 19054528].
  • 14. Lane MM, Czyzewski DI, Chumpitazi BP, Shulman RJ. Reliability and validity of a Modified Bristol Stool Form Scale for children. J Pediatr. 2011;159(3):437-441 e1. doi: 10.1016/j.jpeds.2011.03.002. [PubMed: 21489557]. [PubMed Central: PMC3741451].
  • 15. Chumpitazi BP, Lane MM, Czyzewski DI, Weidler EM, Swank PR, Shulman RJ. Creation and initial evaluation of a Stool Form Scale for children. J Pediatr. 2010;157(4):594-7. doi: 10.1016/j.jpeds.2010.04.040. [PubMed: 20826285]. [PubMed Central: PMC2937014].
  • 16. Ghosh A, Griffiths DM. Rectal biopsy in the investigation of constipation. Arch Dis Child. 1998;79(3):266-8. doi: 10.1136/adc.79.3.266. [PubMed: 9875026]. [PubMed Central: PMC1717694].
  • 17. Leung AK, Chan PY, Cho HY. Constipation in children. Am Fam Physician. 1996;54(2):611-8. 627. [PubMed: 8701840].
  • 18. Fishman L, Lenders C, Fortunato C, Noonan C, Nurko S. Increased prevalence of constipation and fecal soiling in a population of obese children. J Pediatr. 2004;145(2):253-4. doi: 10.1016/j.jpeds.2004.04.022. [PubMed: 15289779].
  • 19. Philichi L. Management of childhood functional constipation. J Pediatr Health Care. 2018;32(1):103-11. doi: 10.1016/j.pedhc.2017.08.008. [PubMed: 29229066].
  • 20. Chao HC, Chen SY, Chen CC, Chang KW, Kong MS, Lai MW, et al. The impact of constipation on growth in children. Pediatr Res. 2008;64(3):308-11. doi: 10.1203/PDR.0b013e31817995aa. [PubMed: 18414138].
  • 21. Koppen IJN, Velasco-Benítez CA, Benninga MA, Di Lorenzo C, Saps M. Is there an association between functional constipation and excessive bodyweight in children? J Pediatr. 2016;171:178-1820. doi: 10.1016/j.jpeds.2015.12.033.
  • 22. Dehghani SM, Karamifar H, Imanieh MH, Mohebbi E, Malekpour A, Haghighat M. Evaluation of the growth parameters in children with chronic functional constipation. Ann Colorectal Res. 2013;1(2):55-9. doi: 10.5812/acr.11979.
  • 23. Pawlowska K, Umlawska W, Iwanczak B. A link between nutritional and growth states in pediatric patients with functional gastrointestinal disorders. J Pediatr. 2018;199:171-7. doi: 10.1016/j.jpeds.2018.02.069. [PubMed: 29709346].
  • 24. Santucci NR, Hyman PE. Do functional gastrointestinal disorders affect growth and nutrition? J Pediatr. 2018;199:9-10. doi: 10.1016/j.jpeds.2018.04.006. [PubMed: 29731354].

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