1 Department of Laboratory Medicine, Fujian Provincial Maternity and Children Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China
2 Department of Laboratory Medicine, Medical Technology and Engineering College, Fujian Medical University, Fuzhou, China
3 Department of Neonatology, Fujian Provincial Maternity and Children Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China
4 The fourth ward, Fuzhou Tuberculosis Prevention and Cure Hospital, Fuzhou, China
Corresponding Authors:
Article information
Iranian Journal of Pediatrics: June 2017, 27 (3); e9448
To Cite:
Xue
H, Xue
X, Yang
C, Chen
Q, Lin
N, et al. Low Serum Mannose Binding Lectin (MBL) Levels and -221 YX Genotype of MBL2 Gene Are Susceptible to Neonatal Sepsis in the Chinese Han Population,
Iran J Pediatr.
2017
; 27(3):e9448.
doi: 10.5812/ijp.9448.
1.
Lawn JE, Cousens S, Zupan J, Lancet Neonatal Survival Steering T. 4 million neonatal deaths: when? Where? Why? Lancet. 2005; 365(9462): 891-900[DOI][PubMed]
2.
Adib M, Bakhshiani Z, Navaei F, Saheb Fosoul F, Fouladi S, Kazemzadeh H. Procalcitonin: a reliable marker for the diagnosis of neonatal sepsis. Iran J Basic Med Sci. 2012; 15(2): 777-82[PubMed]
3.
Krishnaveni P, Vanitha M, Pradeep G. Estimation of serum amyloid A protein in neonatal sepsis: a prospective study. Int J Med Sci Public Health. 2016; 5(8): 1665[DOI]
4.
Angeletti S, Battistoni F, Fioravanti M, Bernardini S, Dicuonzo G. Procalcitonin and mid-regional pro-adrenomedullin test combination in sepsis diagnosis. Clin Chem Lab Med. 2013; 51(5): 1059-67[DOI][PubMed]
5.
Zurek J, Vavrina M. Procalcitonin Biomarker Kinetics to Predict Multiorgan Dysfunction Syndrome in Children With Sepsis and Systemic Inflammatory Response Syndrome. Iran J Pediatr. 2015; 25(1)[DOI][PubMed]
6.
de Benedetti F,
Auriti C,
D'Urbano LE,
Ronchetti MP,
Rava L,
Tozzi A,
et al.
Low serum levels of mannose binding lectin are a risk factor for neonatal sepsis. Pediatr Res. 2007; 61(3): 325-8[DOI][PubMed]
7.
Ozkan H,
Koksal N,
Cetinkaya M,
Kilic S,
Celebi S,
Oral B,
et al.
Serum mannose-binding lectin (MBL) gene polymorphism and low MBL levels are associated with neonatal sepsis and pneumonia. J Perinatol. 2012; 32(3): 210-7[DOI][PubMed]
9.
Giubergia V,
Salim M,
Fraga J,
Castiglioni N,
Sen L,
Castanos C,
et al.
Post-infectious bronchiolitis obliterans and mannose-binding lectin insufficiency in Argentinean children. Respirology. 2015; 20(6): 982-6[DOI][PubMed]
10.
Mills TC,
Chapman S,
Hutton P,
Gordon AC,
Bion J,
Chiche JD,
et al.
Variants in the Mannose-binding Lectin Gene MBL2 do not Associate With Sepsis Susceptibility or Survival in a Large European Cohort. Clin Infect Dis. 2015; 61(5): 695-703[DOI][PubMed]
11.
Zhang AQ,
Yue CL,
Pan W,
Gao JW,
Zeng L,
Gu W,
et al.
Mannose-binding lectin polymorphisms and the risk of sepsis: evidence from a meta-analysis. Epidemiol Infect. 2014; 142(10): 2195-206[DOI][PubMed]
12.
Frakking FN,
Brouwer N,
van Eijkelenburg NK,
Merkus MP,
Kuijpers TW,
Offringa M,
et al.
Low mannose-binding lectin (MBL) levels in neonates with pneumonia and sepsis. Clin Exp Immunol. 2007; 150(2): 255-62[DOI][PubMed]
13.
Ozdemir O, Dinleyici EC, Tekin N, Colak O, Aksit MA. Low-mannose-binding lectin levels in susceptibility to neonatal sepsis in preterm neonates with fetal inflammatory response syndrome. J Matern Fetal Neonatal Med. 2010; 23(9): 1009-13[DOI][PubMed]
14.
Gao DN,
Zhang Y,
Ren YB,
Kang J,
Jiang L,
Feng Z,
et al.
Relationship of serum mannose-binding lectin levels with the development of sepsis: a meta-analysis. Inflammation. 2015; 38(1): 338-47[DOI][PubMed]
15.
Levy MM,
Artigas A,
Phillips GS,
Rhodes A,
Beale R,
Osborn T,
et al.
Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study. Lancet Infect Dis. 2012; 12(12): 919-24[DOI][PubMed]
16.
Chen QQ, Dong F, Chen M, Gao F, Liu QC. Arg194–Arg399 haplotype of XRCC1 gene is susceptible to lung cancer in the Han population. Eur J Inflam. 2016; 14(1): 27-33
17.
Chen Q,
Xue H,
Chen M,
Gao F,
Xu J,
Liu Q,
et al.
High serum trypsin levels and the -409 T/T genotype of PRSS1 gene are susceptible to neonatal sepsis. Inflammation. 2014; 37(5): 1751-6[DOI][PubMed]
18.
Zinyama-Gutsire RB,
Chasela C,
Madsen HO,
Rusakaniko S,
Kallestrup P,
Christiansen M,
et al.
Role of mannose-binding lectin deficiency in HIV-1 and schistosoma infections in a rural adult population in Zimbabwe. PLoS One. 2015; 10(4)[DOI][PubMed]
19.
Das BK, Panda AK. MBL-2 polymorphisms (codon 54 and Y-221X) and low MBL levels are associated with susceptibility to multi organ dysfunction in P. falciparum malaria in Odisha, India. Front Microbiol. 2015; 6: 778[DOI][PubMed]
20.
Prencipe G,
Azzari C,
Moriondo M,
Devito R,
Inglese R,
Pezzullo M,
et al.
Association between mannose-binding lectin gene polymorphisms and necrotizing enterocolitis in preterm infants. J Pediatr Gastroenterol Nutr. 2012; 55(2): 160-5[DOI][PubMed]
21.
Auriti C,
Prencipe G,
Inglese R,
Azzari C,
Ronchetti MP,
Tozzi A,
et al.
Role of mannose-binding lectin in nosocomial sepsis in critically ill neonates. Hum Immunol. 2010; 71(11): 1084-8[DOI][PubMed]
22.
Liu L, Ning B. The role of MBL2 gene polymorphism in sepsis incidence. Int J Clin Exp Pathol. 2015; 8(11): 15123-7[PubMed]
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