Nephrotic Syndrome Following H1N1 Influenza in a 3-Year-Old Boy

AUTHORS

Francesca del Bufalo 1 , Giorgia Bottaro 1 , Pio Liberatore 2 , Ottavio Vitelli 1 , Antonio Gatto 2 , Pietro Ferrara 3 , *

1 Campus Bio-Medico University, Rome, Italy

2 Department of Pediatric Sciences, A. Gemelli University Hospital, Rome, Italy

3 Department of Pediatric Sciences, A. Gemelli University Hospital, Rome & Campus Bio-Medico University, Rome, Italy

How to Cite: del Bufalo F, Bottaro G, Liberatore P, Vitelli O, Gatto A, et al. Nephrotic Syndrome Following H1N1 Influenza in a 3-Year-Old Boy , Iran J Pediatr. 2015 ; 22(2):265-268.

ARTICLE INFORMATION

Iranian Journal of Pediatrics: 22 (2); 265-268
Published Online: June 30, 2012
Article Type: Case Report
Received: February 25, 2011
Accepted: November 15, 2011

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Abstract

Background: The pandemic influenza A/H1N1, spread through the world in 2009, producing a serious epidemic in Italy. Complications are generally limited to patients at the extremes of age (<6 months or >65 years) and those with comorbid medical illness. The most frequent complications of influenza involve the respiratory system.
Case Presentation: A 3-year-old boy with a recent history of upper respiratory tract infection developed a nephrotic syndrome. Together with prednisone, furosemide and albumin bolus, a therapy with oseltamivir was started since the nasopharyngeal swab resulted positive for influenza A/H1N1. Clinical conditions and laboratory findings progressively improved during hospitalization, becoming normal during a 2 month follow up.
Conclusion: The possibility of a renal involvement after influenza A/H1N1 infection should be considered.

Keywords

Influenza A H1N1 Nephrotic Syndrome Oseltamivir Prednisone

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